
5-HT3 antagonist 3
CAS No. 120635-47-4
5-HT3 antagonist 3( —— )
Catalog No. M26032 CAS No. 120635-47-4
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 264 | Get Quote |
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5MG | 404 | Get Quote |
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10MG | 593 | Get Quote |
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25MG | 888 | Get Quote |
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50MG | 1251 | Get Quote |
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100MG | 1692 | Get Quote |
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500MG | 3402 | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product Name5-HT3 antagonist 3
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NoteResearch use only, not for human use.
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Brief Description5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist.
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Description5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).(In Vitro):Serotonin (5-HT), involved in numerous physiological and pathophysiological processes, interacts with various distinct membrane receptors.
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In VitroSerotonin (5-HT), involved in numerous physiological and pathophysiological processes, interacts with various distinct membrane receptors.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptorβ1 integrin
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Research Area——
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Indication——
Chemical Information
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CAS Number120635-47-4
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Formula Weight319.408
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Molecular FormulaC20H21N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1nccn1CC1CCc2c(C1=O)c1cccc3CCCn2c13
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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GSK163090
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
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PRX-07034
PRX-07034 is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents.?PRX-07034 is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (≥100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors.